• Growth Factor Serum
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ZO Skin Health

Growth Factor Serum

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Firmer, smoother, more supple looking skin, built week by week.

Your skin has lost some of its bounce, and fine lines are becoming part of the picture.

Growth Factor Serum helps skin look denser, firmer and smoother, with more radiance and hydration. It pairs human comparable growth factors with plant and enzymatically derived growth factors. A peptide that softens the look of expression lines and ZPRO, which helps skin look plumper and more hydrated, complete the formula.

Who It Is For

Adults who want firmer, denser looking skin and a smoother, more radiant surface.

Not Acne Safe

What You Will See, and When

In ZO's 12 week clinical study of 46 adults aged 44 to 74, visible radiance and texture improved 42%, hydration 26% and elasticity 16%, and 98% said their skin looked rejuvenated.

How to Use

Every night on clean, dry skin. Smooth one to two pumps over your face, neck and around your eyes, after cleansing and before moisturizer. Wear sunscreen every morning to protect your results.

The Science

Growth factors help skin look firmer, denser and smoother.

In published research, topical growth factors improved the look of fine lines and texture, most clearly around the eyes. Reviews of the research since then support growth factors as a way to improve the look of aging skin.

Questions

Where does it go in my routine?At night, after cleansing (and after Plated, if you use it), before your other serums and moisturizer.
Can I use it around my eyes?Yes. ZO directs it for face, neck and the eye area.
Can I use it with retinol?Yes. Apply your retinol at night and this serum over it.

Why a Routine Made for You Works Better

General advice is written for everyone, so it has to assume nothing about you. It can tell you what is safe. It cannot tell you what will work for your skin.

Skin changes when it is challenged just enough, then given time to recover and adapt. That amount is different for every person, and it moves as your skin gets stronger. Ask too much and your skin spends its energy recovering instead of improving. Ask too little and nothing changes. Finding that point for you, and moving it at the right time, is where results come from.

Where that point sits depends on:

  • Your skin: its history, how it reacts, and what it is doing today
  • Your health: hormones, medications, pregnancy and any condition that changes how skin behaves
  • Your lifestyle: sleep, stress, diet, sun, exercise and climate
  • Your routine: what you use now, and what has and has not worked before
  • Your goals: what you most want to change
  • Your expectations and timeline: how soon you want to see change, and what is realistic for your skin
  • Your consistency: how much time and how many steps you will keep up with, because the best routine is the one you actually do
  • Your treatments: what you have had and what you have planned

A skin therapist weighs all of this, builds a routine you can keep, and adjusts it as your skin responds. That is why we guarantee our products when they are part of a routine designed by one of our skin therapists. If you have been reading general advice, bring your questions. We will help you sort out what applies to you and what does not.

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Key Ingredients

Human comparable growth factorsSupport the look of skin renewal and vitality
Plant and enzymatically derived growth factorsHelp restore the look of density and firmness
Dipeptide diaminobutyroyl benzylamide diacetateSoftens the look of expression lines
ZPROHelps skin look plumper and more hydrated
Full Ingredient List

Aqua/Water/Eau, Dimethicone, Butylene Glycol, Glycerin, Caprylyl Methicone, Dimethicone/PEG-10/15 Crosspolymer, PEG-12 Dimethicone/PPG-20 Crosspolymer, Dimethicone/Vinyl Dimethicone Crosspolymer, 1,2-Hexanediol, Caprylyl Glycol, Sodium Hyaluronate, Sodium Chloride, Dimethicone Crosspolymer, Lactobacillus Ferment, Scutellaria Baicalensis Root Extract, Sodium Citrate, Hydrolyzed Sericin, Phospholipids, Acetyl Glutamine, Lecithin, Buddleja Davidii Meristem Cell Culture, Cordyceps Militaris Mycelium Extract, Glycyrrhiza Uralensis (Licorice) Root Extract, Dipropylene Glycol, Pentylene Glycol, Xanthan Gum, Beta-Glucan, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Lactobacillus/Panax Ginseng Root Ferment Filtrate, Hexylene Glycol, Phenoxyethanol, Potassium Sorbate, Tocopherol, Disodium Acetyl Glucosamine Phosphate, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-11, Sh-Polypeptide-9, Bacillus/Folic Acid Ferment Filtrate Extract, Hexamethylindanopyran, Terpineol, Tetramethyl Acetyloctahydronaphthalenes, Fragrance/Parfum.

References

1. Fitzpatrick RE, Rostan EF. Reversal of photodamage with topical growth factors: a pilot study. J Cosmet Laser Ther. 2003;5(1):25-34. doi:10.1080/14764170310000817
2. Aldag C, Nogueira Teixeira D, Leventhal PS. Skin rejuvenation using cosmetic products containing growth factors, cytokines, and matrikines: a review of the literature. Clin Cosmet Investig Dermatol. 2016;9:411-419. doi:10.2147/CCID.S116158
3. ZO Skin Health clinical data: 12 week clinical study, 46 subjects aged 44 to 74 (brand published).

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Growth Factor Serum

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Sun damage, fine lines or uneven tone, and skin that doesn't clog or break out? Try this routine.